Drug Deep Dives

One drug. What actually happens.

A closer look at the drugs we use every day — mechanism, pharmacology, clinical reasoning, and the details that matter at the bedside.

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001 Aug 2026
Dexmedetomidine
The sedative that lets a patient wake up when you talk to them — and punishes anyone who rushes it. Highly selective α2-agonist with genuine analgesic, opioid-sparing, and delirium-sparing properties.
Sedatives Pediatric ICU TIVA
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002 Aug 2026
Propofol
The white emulsion that behaves so well, so often, that the one time it doesn't can catch you off guard. The default IV induction agent — fast, clean, and unforgiving of complacency.
Induction Sedatives Pediatric TIVA
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003 Sep 2026
Lidocaine
The local anaesthetic used so often, in so many forms, that its dose limits are the ones most likely to be assumed rather than checked. Fast onset, versatile, and unforgiving of arithmetic errors.
Local Cardiac Pediatric Regional Airway
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004 Sep 2026
Ketamine
The one induction agent that supports blood pressure instead of dropping it — with a reputation that often precedes the pharmacology. Dissociative, bronchodilating, and genuinely haemodynamic-supportive.
Induction Sedatives Pediatric Trauma ICU
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005 Sep 2026
Sevoflurane
Sweet-smelling enough to breathe a child to sleep, and ordinary enough that the calculation behind every vaporiser dial rarely gets a second thought. The default volatile agent, re-examined.
Volatile Induction Pediatric Neuro Maintenance
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006 Sep 2026
Magnesium Sulfate
An old, inexpensive electrolyte that ended up as a seizure prophylactic, a treatment for torsades de pointes, and an anaesthetic adjunct — three separate careers under one name.
Obstetric Cardiac ICU Analgesic Resuscitation
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